4 New Research Articles on Potential Prostate Cancer Breakthroughs!

Hi Guys,

Here are 4 very interesting articles on new and potential breakthroughs in dealing with finding a cure for Prostate Cancer.  Some day this will happen!

Article #1 deals with cancer cells gradually mutating over time to overwhelm the ability of cells to control growth.  Large scale reshuffling of DNA driving the development of prostate cancer!  Article #2 deals with genetic variants that could account for an 18 percent reduction in the number of men who likely would have undergone unnecessary biopsies.  Article #3  Shc, pronounced “schick,” plays a key role in activating signals which lead to cell proliferation (and cancer) when cells are stimulated, however it unexpectedly turns out to be a tumor-suppressor!   Article #4  Researchers have discovered that a genetically engineered Newcastle disease virus, which harms chickens but not humans, kills prostate cancer cells of all kinds, including hormone-resistant cancer cells.

1)  Prostate Cancer Gains Powerful Advantage With Abrupt Intervals Of Complex, Large Scale DNA Reshuffling

Article Date: 28 Apr 2013

Cancer is typically thought to develop after genes gradually mutate over time, finally overwhelming the ability of a cell to control growth. But a new closer look at genomes in prostate cancer by an international team of researchers reveals that, in fact, genetic mutations occur in abrupt, periodic bursts, causing complex, large scale reshuffling of DNA driving the development of prostate cancer”.  Full Story A

2)  Using Genetic Variants To Personalize Prostate Cancer Screenings

Article Date: 26 Apr 2013

“Personalized PSA testing using genetic variants could account for an 18 percent reduction in the number of men who likely would have undergone unnecessary biopsies, according to the study. It will be published in the May 2013 issue of The Journal of Urology”.  Full Story B

3)  Same Protein That Fires Up Cancer-Promoting Erk Also Blocks Its Activation

Article Date: 23 Apr 2013

“Shc, pronounced “schick,” plays a key role in activating signals which lead to cell proliferation (and cancer) when cells are stimulated, however it unexpectedly turns out to be a tumor-suppressor, keeping Erk under wraps when a cell is less active, said senior author John Ladbury, Ph.D., professor in MD Anderson’s Department of Biochemistry and Molecular Biology.  Overexpression of Erk occurs in many types of cancer, including ovarian and prostate cancer and Hodgkin lymphoma, so cellular control of its activity is important.  Full Story C

4)  Study Finds Bird Virus Promising For Prostate Cancer Treatment

Article Date: 11 Apr 2013

“A study at the Virginia-Maryland Regional College of Veterinary Medicine has identified a chicken-killing virus as a promising treatment for prostate cancer in humans.   Researchers have discovered that a genetically engineered Newcastle disease virus, which harms chickens but not humans, kills prostate cancer cells of all kinds, including hormone-resistant cancer cells. The work of Dr. Elankumaran Subbiah, associate professor of virology in the Department of Biomedical Sciences and Pathobiology”.

Full Story D

“Make Every Day Count” !

Craig Becker

The New Denver Men’s Club

 University Prostate Cancer Support Group, Inc.
Group Leader


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