(2) Excellent PCa Articles From “Prostate Cancer Topic Resource Center”!

Hi Guys,

(2) very interesting articles.   Article #1 deals with how early BPA exposure increases prostate cancer risk in plastic bottles.  Article #2 deals with a new approach of combining PET with magnetic resonance (PET/MR) was shown to be more sensitive—compared with PET/CT—in detecting recurrent prostate cancer.

1)  Study: BPA Exposure in Developing Prostate Increases Later Cancer Risk !

By Anna Azvolinsky, PhD1 | June 20, 2013   Gail Prins, PhD, professor of urology and physiology at the College of Medicine at the University of Illinois in Chicago, and colleagues provided evidence for one of the first direct links between low-dose exposure to BPA during the development of rats and the later development of prostate cancer. Estrogens(Drug information on estrogens) have been implicated in carcinogenesis, and BPA exposure during prenatal development has been thought to be a culprit in increases in prostate cancer rates.
Now, Prins and colleagues show that early BPA exposure increases the cancer risk in animal models of human prostate cancer. Prins presented the results at the Endocrine Society’s Annual Meeting & Expo in June.“The most important findings are that the human prostate epithelium responds in a similar manner as previous studies found in rodents,” Prins told Cancer Network. The results show that even low doses of BPA could cause early, subtle changes that can have latent consequences. 

2)  PET/MR Outperforms PET/CT in Detecting Prostate Cancer Recurrence

By Anna Azvolinsky, PhD1 | June 25, 2013The current so-called imaging gold standard for prostate cancer is the positron emission tomography combined with computed tomography (PET/CT). But the clinical need to identify small tumors is continuing to push imaging technology forward.

Siemens Biograph mMR

In a recent study, the new approach of combining PET with magnetic resonance (PET/MR) was shown to be more sensitive—compared with PET/CT—in detecting recurrent prostate cancer. The PET/MR approach detected more areas of recurrent metastatic disease, including more bone and lymph node metastasis compared with PET/CT.

“The main difference was the substantial higher detection rate of local recurrences in PET/MR compared to PET/CT,” said lead author Matthias Eiber, MD, of the Technical University Munich, Germany.

The results were presented at the Society of Nuclear Medicine and Molecular Imaging Annual Meeting held in Vancouver.

A PET scan shows how tissues and organs in the body are functioning thanks to a radioactive tracer that is injected into the patient via the bloodstream. The MRI technology gives an image of soft tissues, bone, and organs in the body.

MR imaging is based on the amount of water in the body and results in finer detailed imaging compared with the x-ray–based CT scan.

PET/MR scanning takes longer than PET/CT but was found to be tolerable by patients. Another benefit of PET/MR is the lower radiation exposure compared with PET/CT, a likely important factor for patients who get sequential scans of their cancer over a relatively short period of time. The study found that PET/MR has the potential to reduce radiation exposure by as much as 80% compared with the PET/CT approach.

PET/MR Outperforms PET/CT

“I would rather die making things better than live doing nothing”!

Craig Becker

The New Denver Men’s Club

 University Prostate Cancer Support Group, Inc.
Group Leader

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3 thoughts on “(2) Excellent PCa Articles From “Prostate Cancer Topic Resource Center”!

  1. Survival of prostate cancer (triple hormone blockade treatment then radiation with another round of treatment) ten years ago. My issue now is low testosterone (52 at last blood work). Really affecting my energy level. Two doctors have told me “no treatment as might cause the cancer to return, one who wanted to give me shots and permanent injections to increase the level of testosterone. Any research on this topic? Thanks

    • Hi Gerald, As you know, PCa cells are fed by your bodies Testo. With your previous case of having prostate cancer, I would be afraid to introduce more Testo into your system for a chance to feel better. In my opinion, the reward would not be worth the chance to feed an occurrence of prostate cancer.
      Best of luck,
      Craig Becker

      • Thanks – I cannot find any medical research on this topic. But unless I hear otherwise from a source I feel I can trust, I will just go to bed early!!

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