(4) Exciting Potential Prostate Cancer Breakthroughs!

Hi Guys,

Article #1 is especially interesting as Monash University discovers that certain prostate cancer cells survive androgen withdrawal treatment and can be used as potential targets for future therapy before the cancer becomes aggressive or incurable.  Article #2 is about China’s extremely low PCa rate,  The Santa Monica, California-based Prostate Cancer Foundation wants to know why 17% of American males – black men in particular – seem to be at risk of developing prostate cancer, while the disease affects only 2% of rural Chinese men.  Now, the Prostate Cancer Foundation has dedicated a pool of money to encourage Chinese researchers to tackle questions that might lead to cancer-beating breakthroughs.  Article #3 is a follow up on article#2 from: PubMed.

Article #4 deals with It’s In Your Genes: New breakthrough in genetics helps families with a history of cancer predict and prevent the world’s most dreaded disease.  At the root of it is God’s own jigsaw puzzle: The human genome, or the entire set of inheritable traits in our cells that make us who we are. With scientists mapping more genes in the human body, cancer genetics is now one of the fastest expanding medical specialties and it is altering clinical practice, with oncologists and geneticists targeting genes that are ‘faulty’.

1) Breakthrough in prostate cancer research

31 May 2013  “Singapore: Researchers in Monash University, Australia, have found prostate cancer cells that survive androgen withdrawal treatment. Previously unidentified, these cells are potential targets for future treatments. As they are present early in disease development, there is the possibility of therapy before the cancer reaches the aggressive, incurable stage. For advanced cases, the best available treatment for prostrate cancer involves drugs that effectively mimic castration and so deprive the tumour of the male hormones that cause it to grow. Androgen deprivation therapy is highly effective; however, the tumour eventually becomes resistant to the treatment and regrows in an incurable form”.

2)China on Front Lines of Fight Against Prostate Cancer

“Cancer and cardiovascular diseases in particular are drawing research money, as drug makers examine how localizing research might pay off in treatments for one of the fastest-growing pharmaceutical markets. The work is drawing increasing respect: The U.S.-based National Foundation for Cancer Research recently selected two Chinese researchers to share an annual award for their work combining traditional Chinese medicine and Western techniques to treat a form of leukemia”.

Full Story: China on Front Lines of Fighting PCa

3) Follow up-Prostate cancer research in China.

PubMed.  2013 May;15  “Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China.Prostate cancer (PCa) research in China has been on a rocketing trend in recent years. The first genome-wide association study (GWAS) in China identified two new PCa risk associated single nucleotide polymorphisms (SNPs). Next generation sequencing is beginning to be used, yielding novel findings: gene fusions, long non-coding RNAs and other variations. Mechanisms of PCa progression have been illustrated while various diagnosis biomarkers have been investigated extensively. Personalized therapy based on genetic factors, nano-medicine and traditional Chinese medicine has been the focus of experimental therapeutic research for PCa. This review intends to shed light upon the recent progress in PCa research in China and points out the possible breakthroughs in the future”.

Full Story: Follow up, “Prostate cancer research in China”

4)  It’s In Your Genes

“The war on cancer has turned a new corner. And radical new genetic management of the disease, even before cancer strikes, is catching on. The Tata Memorial Centre (TMC) in Mumbai, where Peshwe was a patient, has put 35 members of Vaze’s family through genetic tests: To predict their cancer risk and prevent it on time.  Going by statistics, just 10 per cent of all cancers are inherited. But by absolute numbers, it’s no less than 50,000 lives each year in India, says Dr Rajiv Sarin, who set up one of India’s first cancer genetics units at TMC with support from the Indian Council of Medical Research. As the geography of investigation shifts from organs, tissues and cells to the DNA, it becomes increasingly possible for families with a history of cancer to buy their way out of destiny”. Full Story: “It’s In Your Genes”

Craig Becker

The New Denver Men’s Club

 University Prostate Cancer Support Group, Inc.
Group Leader

“The best way to forget your own problems is help others solve theirs”!


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