(2) potential breakthrough articles! ethinylestradiol for castration-resistant prostate cancer

 

Hi Guys,

Check out the promising results of this study with only 14 patients and the second article they call a major breakthrough!

ut-logo websitePublished on 18 July 2014

1)  Oral ethinylestradiol administration may have efficacy for CRPC without severe adverse events. Ethinylestradiol may be one of the selective drugs for CRPC patients who do not wish to undergo intravenous chemotherapy or become resistant to docetaxel.

“RESULTS: All patients had already been treated with a combined androgen blockade (CAB), 8 patients had been treated with docetaxel, 9 patients with tegafur-uracil, 4 patients with estramustine phosphate sodium. Age and prostate-specific antigen (PSA) at prescription of ethinylestradiol was 55-85 (median 75.5) and 0.784-508.7 ng/ml (median 4.842 ng/ml). Thirteen patients (92.9%) achieved a decline in PSA, 8 patients (57.1%) achieved a decline in PSA > 50%. Time to progression was 0-18 months (median 7 months), and there were no severe adverse events including venous thromboembolic diseases”.  Full Story: efficacy-of-ethinylestradiol-for-castration-resistant-prostate-cancer

2)  Structure of protein vital to cancer development is mapped   Monday 21 July 2014

A major breakthrough has been made by scientists who have successfully managed to map out the structure of a complicated protein that is regarded to be one of the most important in cell division. This knowledge could be used in the future in the development of cancer drugs”.Cancer cellsThousands of copies of cancer cells are created during cell division. New research into the APC/C may eventually put a stop to this”!  “The new study is a major step forward in our understanding of cell division. When the process goes awry it is a critical difference that separates cancer cells from their healthy counterparts. Understanding exactly how cancer cells divide inappropriately is crucial to the discovery of innovative cancer treatments to improve outcomes for cancer patients”. Full Story: Structure of protein vital to cancer development is mapped

I’m not afraid of death…….. staying alive is much harder! (Craig R. Becker)

Craig Becker

The New Denver Men’s Club

Blog: https://newdenvermensclub.wordpress.com/ “Men Fighting Cancer To Win”

 

 

 

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One thought on “(2) potential breakthrough articles! ethinylestradiol for castration-resistant prostate cancer

  1. Hi Craig, Great Post! Getting a little nerveous about results on weds, after ignoring for 3 months. Hope I said that right yesterday that I get up in the night to do zytiga bcse of fasting. I think the xtandi zytiga combo will work well for you , It is all I have been on for the past year, also good to know you do not need luppron while on this combo as it will make your t undetectable. I like your post script. Dan

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